Oligo & Peptide Synthesis

Ajinomoto Bio-Pharma Services offers high quality, scalable, custom oligonucleotides and peptides. Our knowledgeable and highly skilled scientists employ both traditional solid phase production and our innovative AJIPHASE® synthesis technology to seamlessly develop and manufacture highly-pure DNA/RNA oligos, PMOs and peptide chains.

Solid Phase Manufacturing We offer small scale, fast manufacturing of custom oligos, including process development and analytical testing for either cGMP or non-GMP use. With a synthesis range of µg to 200 g, we provide a wide range of solid phase DNA and RNA chains. In April 2019, our new plant will be operational, providing the capacity to synthesize up to 10 kg.

  • Small scale custom oligonucleotides
  • Long RNA chains
  • Long chimera DNA/RNA chains by enzymatic ligation

AjiPhase Manufacturing AJIPHASE® is a robust, proven technology for developing and manufacturing (under cGMP) large scale oligonucleotides and peptides. The technology is a hybrid of traditional solid phase and solution phase synthesis, using an anchor in place of a resin. This innovative change allows for processing to move from a solution to a solid phase and be filtered out all in a single vessel. This process is highly scalable providing highly cost-effective and pure oligonucleotides and peptides, with less waste byproducts.

  • Large scale DNA/RNA Oligonucleotides
  • Phosphorodiamidate Morpholino Oligonucleotides (PMO)
  • Long chain peptides